{"id":28,"date":"2022-02-25T16:21:06","date_gmt":"2022-02-25T21:21:06","guid":{"rendered":"https:\/\/home.hamptonu.edu\/cancerresearch\/?page_id=28"},"modified":"2022-02-25T16:27:16","modified_gmt":"2022-02-25T21:27:16","slug":"research","status":"publish","type":"page","link":"https:\/\/home.hamptonu.edu\/cancerresearch\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"28\" class=\"elementor elementor-28\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-27f30eb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"27f30eb\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b59b073\" data-id=\"b59b073\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a600246 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a600246\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-10514a0\" data-id=\"10514a0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0edf5de elementor-widget elementor-widget-text-editor\" data-id=\"0edf5de\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h1 style=\"margin-bottom: 0px; padding: 5px 15px; font-size: 27.2px; font-family: georgia, serif; color: #003384; letter-spacing: 1px; font-weight: normal; width: 768px; border-bottom: 1px dotted #cccccc; font-style: normal;\">Publications<\/h1><div style=\"margin: 0px; padding: 9.59375px; clear: both; color: #000000; font-family: Arial, Helvetica, sans-serif; font-size: 16px;\"><div style=\"margin: 2.8125px; padding: 2.8125px; width: 926.688px; float: left;\"><ol style=\"margin: 20px 40px;\"><li style=\"padding-bottom: 10px;\">Mason TE,\u00a0<strong style=\"margin: 0px; padding: 0px;\">Ricks-Santi L,<\/strong>\u00a0Chen W, Apprey V, Joykutty J, Ahaghotu C, Kittles R, Bonney G, Dunston GM.\u00a0\u00a0<strong style=\"margin: 0px; padding: 0px;\"><em style=\"margin: 0px; padding: 0px;\">Association of CD14 variant with prostate cancer in African American men.\u00a0<\/em><\/strong>Prostate.2010 Feb 15;70(3):262-9<\/li><li style=\"padding-bottom: 10px;\"><strong style=\"margin: 0px; padding: 0px;\">Ricks-Santi L,<\/strong>\u00a0Mason T,\u00a0 Apprey V, Ahaghotu C,\u00a0 McLaughlin A,\u00a0 Josie D,\u00a0 Bonney G, Dunston GM,\u00a0<strong style=\"margin: 0px; padding: 0px;\"><em style=\"margin: 0px; padding: 0px;\">Pro72Arg polymorphism and prostate cancer in men of African descent<\/em><\/strong>. Prostate. 2010 Dec 1;70 (16):1739-45.<\/li><li style=\"padding-bottom: 10px;\"><strong style=\"margin: 0px; padding: 0px;\">L. Ricks-Santi,<\/strong>\u00a0Lara Sucheston, Yang Yang, Jo L Freudenheim, Claudine Isaacs, Marc D. Schwartz , Ramona Dumitrescu, Catalin Marian, Jing Nie, Dominica Vito, Stephen Edge, Peter G. Shields.\u00a0<strong style=\"margin: 0px; padding: 0px;\"><em style=\"margin: 0px; padding: 0px;\">Association of Rad51 polymorphism with DNA repair in BRCA1 Mutation Carriers and Sporadic Breast Cancer Risk.<\/em><\/strong>\u00a0BMC Cancer. 2011 Jun 27;11:278. PMID: 21708019<\/li><li style=\"padding-bottom: 10px;\">James Lindesay, Tshela E Mason,\u00a0<strong style=\"margin: 0px; padding: 0px;\">Luisel Ricks-Santi<\/strong>, William Hercules, Philip Kurian, Georgia M Dunston.\u00a0<strong style=\"margin: 0px; padding: 0px;\"><em style=\"margin: 0px; padding: 0px;\">A New Biophysical Metric for Interrogating the Information Content in Human Genome Sequence Variation: Proof of Concept.\u00a0<\/em><\/strong>Physics Archives. 2011 August 17, 2011<\/li><li style=\"padding-bottom: 10px;\">James Lindesay, Tshela E Mason,\u00a0<strong style=\"margin: 0px; padding: 0px;\">Luisel Ricks-Santi<\/strong>, William Hercules, Philip Kurian, Georgia M Dunston.\u00a0<strong style=\"margin: 0px; padding: 0px;\"><em style=\"margin: 0px; padding: 0px;\">A New Biophysical Metric for Interrogating the Information Content in Human Genome Sequence Variation: Proof of Concept.\u00a0<\/em><\/strong>Journal of Computational Biology and Bioinformatics Research. Accepted November 29, 2011\u00a0\u00a0\u00a0\u00a0\u00a0<\/li><li style=\"padding-bottom: 10px;\"><strong style=\"margin: 0px; padding: 0px;\">L. Ricks-Santi,<\/strong>\u00a0V. Apprey, T. Mason, B. Wilson, M. Abbas, W. Hernandez, S. Hooker, M. Doura, C. AhaghotuG. Bonney G. Dunston, R. Kittles.\u00a0<strong style=\"margin: 0px; padding: 0px;\"><em style=\"margin: 0px; padding: 0px;\">Identification of genetic risk associated with prostate cancer using Ancestry Informative Markers<\/em><\/strong>\u00a0Prostate Cancer and Prostatic Diseases , (17\u00a0July\u00a02012) | doi:10.1038\/pcan.2012.19<\/li><li style=\"padding-bottom: 10px;\">Yasmine M. Kanaan, Desta Beyene, Mohammad Daremipouran, Augustine Mireku-Boateng, Robert Williams, Aaron Jackson, Lucile L. Adams-Campbell, George E. Bonney, Victor Apprey, Marlon G. Daniel, Anthony Wutoh, JoyAnn Phillips Rohan,\u00a0<strong style=\"margin: 0px; padding: 0px;\">Luisel Ricks-Santi<\/strong>\u00a0and Robert L. Copeland Jr.\u00a0<strong style=\"margin: 0px; padding: 0px;\"><em style=\"margin: 0px; padding: 0px;\">Association of Cumulative Ultraviolet Radiation Exposure with Prostate Cancer Risk in a Case-control Study of African-American Men.\u00a0<\/em><\/strong>The Open Prostate Cancer Journal, 2012, 5, 8-14<\/li><li style=\"padding-bottom: 10px;\"><strong style=\"margin: 0px; padding: 0px;\">L. Ricks-Santi,<\/strong>\u00a0J. Nie, C. Marian, H. Ochs-Balcom, M. Trevisan, S. Edge, J. Freudenheim, P. Shields.\u00a0<strong style=\"margin: 0px; padding: 0px;\"><em style=\"margin: 0px; padding: 0px;\">BRCA1 polymorphisms and breast cancer epidemiology in the Western New York Exposures and Breast Cancer (WEB) study<\/em><\/strong>\u00a0Genet Epidemiol. 2013 Jul;37(5):504-11. doi:\u00a0 10.1002\/gepi.21730. Epub 2013 May 14. PMID: 23674270<\/li><li style=\"padding-bottom: 10px;\">Ashwini K. Esnakula,\u00a0<strong style=\"margin: 0px; padding: 0px;\">Luisel J. Ricks-Santi,\u00a0<\/strong>\u00a0Yasmine M. Kanaan, Robert L. DeWitty, Wayne A.I. Frederick, Lori L. Wilson, Victor Apprey, Bert Gold, Julie Sawitzke, Kate M. Im, Tammey J. Naab<strong style=\"margin: 0px; padding: 0px;\"><em style=\"margin: 0px; padding: 0px;\">. Strong association of fascin expression with triple negative breast cancer and basal-like phenotype in African-American women.<\/em><\/strong>\u00a0J Clin Pathol.\u00a02013 Aug 28. doi: 10.1136\/jclinpath-2013-201698; PMID: 23986556<\/li><li style=\"padding-bottom: 10px;\"><strong style=\"margin: 0px; padding: 0px;\">Luisel Ricks-Santi,\u00a0<\/strong>et al.<strong style=\"margin: 0px; padding: 0px;\">\u00a0\u201c<em style=\"margin: 0px; padding: 0px;\">Self-Reported Family History of Cancer Associated with Breast Tumor Clinicopathological features<\/em><\/strong>&#8220;. Accepted with minor revisions to the Journal of the Community Genetics November 2013.<\/li><li style=\"padding-bottom: 10px;\">Gao X,\u00a0<strong style=\"margin: 0px; padding: 0px;\">McDonald JT<\/strong>, Naidu M, Hahnfeldt P, Hlatky L, A Proposed Quantitative Index for Assessing the Potential Contribution of Reprogramming to Cancer Stem Cell Kinetics, Stem Cells International, vol. 2014, Article ID 249309, 8 pages, 2014.<\/li><li style=\"padding-bottom: 10px;\">Sasi SP, Song J, Park D, Enderling H,\u00a0<strong style=\"margin: 0px; padding: 0px;\">McDonald JT<\/strong>, Gee H, Garrity B, Shtifman A, Yan X, Walsh KX, Natarajan M, Kishore R, Goukassian DA. TNF-TNFR2\/p75 Signaling Inhibits Early and Increases Delayed Non-Targeted Effects in Bone Marrow-Derived Endothelial Progenitor Cells. Journal of Biological Chemistry.\u00a0\u00a0<em style=\"margin: 0px; padding: 0px;\">In Press,<\/em>\u00a0<em style=\"margin: 0px; padding: 0px;\">accepted April 7, 2014.<\/em><\/li><li style=\"padding-bottom: 10px;\"><strong style=\"margin: 0px; padding: 0px;\"><span style=\"margin: 0px; padding: 0px;\">McDonald JT<\/span>,<\/strong>\u00a0Briggs C, Szelag H, Peluso M, Schneider D, Perepletchikov A, Lakka Klement, Tuerk I, Hlatky L. Chronic Low Dose-Rate Radiation Down-Regulates Transcription Related to Mitosis and Chromosomal Movement Similar to Acute High Dose in Prostate Cells. International Journal of Radiation Biology, 90(3):231-40; 2014. PMID: 24397407<\/li><li style=\"padding-bottom: 10px;\">Beheshti A, Pinzer BR,\u00a0<strong style=\"margin: 0px; padding: 0px;\"><span style=\"margin: 0px; padding: 0px;\">McDonald JT<\/span>,<\/strong>\u00a0Stampanoni M, Hlatky L. Early Tumor Development Captured Through Non-Destructive, High Resolution Differential Phase Contrast X-ray Imaging. Radiation Research, 180(5):448-54; 2013. PMID: 24125488<\/li><li style=\"padding-bottom: 10px;\">Gao X,\u00a0<strong style=\"margin: 0px; padding: 0px;\"><span style=\"margin: 0px; padding: 0px;\">McDonald JT<\/span>,<\/strong>\u00a0Hlatky L, Enderling H. Acute and fractionated irradiation differentially modulate glioma stem cell division. Cancer Research, 73(5):1481-90; March 2013. PMID: 23269274<\/li><li style=\"padding-bottom: 10px;\"><strong style=\"margin: 0px; padding: 0px;\"><span style=\"margin: 0px; padding: 0px;\">McDonald JT<\/span>,<\/strong>\u00a0Kim K, Norris AJ, Vlashi E, Phillips TM, Lagadec C, Della Donna L, Ratikan J, Szelag H, Hlatky L, McBride WH. Ionizing Radiation Activates the Nrf2 Antioxidant Response. Cancer Research, 70(21):8886-95; 2010. PMID: 20940400<\/li><li style=\"padding-bottom: 10px;\">Kim K, Pollard JM, Norris AJ,\u00a0<strong style=\"margin: 0px; padding: 0px;\"><span style=\"margin: 0px; padding: 0px;\">McDonald JT<\/span>,<\/strong>\u00a0Sun Y, Micewicz E, Pettijohn K, Damoiseaux R, Iwamoto KS, Sayre JW, Price BD, Gatti RA, McBride WH. High Throughput Screening Identifies Two Classes of Antibiotics as Radioprotectors: Tetracyclines and Fluoroquinolones. Clinical Cancer Research, 15(23); 2009. PMID: 19920105<\/li><li style=\"padding-bottom: 10px;\">Vlashi E, Kim K, Lagadec C, Della Donna L,\u00a0<strong style=\"margin: 0px; padding: 0px;\"><span style=\"margin: 0px; padding: 0px;\">McDonald JT<\/span>,<\/strong>\u00a0Eghbali M, Sayre JW, Stefani E, McBride WH, Pajonk F. In Vivo Imaging, Tracking, and Targeting of Cancer Stem Cells. Journal of the National Cancer Institute, 101(5):350-359; 2009. PMID: 19244169<\/li><li style=\"padding-bottom: 10px;\">Brush J, Lipnick SL, Phillips T, Sitko J,\u00a0<strong style=\"margin: 0px; padding: 0px;\"><span style=\"margin: 0px; padding: 0px;\">McDonald JT<\/span>,<\/strong>\u00a0McBride WH. Molecular mechanisms of late normal tissue injury. Seminars in Radiation Oncology, 17(2):121-130; 2006. PMID: 17395042<\/li><li style=\"padding-bottom: 10px;\">Pursell Z,\u00a0<strong style=\"margin: 0px; padding: 0px;\"><span style=\"margin: 0px; padding: 0px;\">McDonald JT<\/span>,<\/strong>\u00a0Mathews CK, Kunkel T. Trace amounts of 8-oxo-dGRP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity. Nucleic Acids Research, 36(7):2174-2181; 2008. PMID: 18276636<\/li><li style=\"padding-bottom: 10px;\"><strong style=\"margin: 0px; padding: 0px;\"><span style=\"margin: 0px; padding: 0px;\">McDonald JT<\/span>,<\/strong>\u00a0West WG, Kearfott KJ. An Evaluation of the Kearny Fallout Meter (KFM), a Radiation Detector Constructed of Commonly Available Household Materials. Health Physics Journal, 87(S2):S52-S57; 2004. PMID: 15551780<\/li><\/ol><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Publications Mason TE,\u00a0Ricks-Santi L,\u00a0Chen W, Apprey V, Joykutty J, Ahaghotu C, Kittles R, Bonney G, Dunston GM.\u00a0\u00a0Association of CD14 variant with prostate cancer in African American men.\u00a0Prostate.2010 Feb 15;70(3):262-9 Ricks-Santi L,\u00a0Mason T,\u00a0 Apprey V, Ahaghotu C,\u00a0 McLaughlin A,\u00a0 Josie D,\u00a0 Bonney G, Dunston GM,\u00a0Pro72Arg polymorphism and prostate cancer in men of African descent. Prostate. 2010 [&hellip;]<\/p>\n","protected":false},"author":105,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-28","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Research - Cancer Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/home.hamptonu.edu\/cancerresearch\/research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research - Cancer Research Center\" \/>\n<meta property=\"og:description\" content=\"Publications Mason TE,\u00a0Ricks-Santi L,\u00a0Chen W, Apprey V, Joykutty J, Ahaghotu C, Kittles R, Bonney G, Dunston GM.\u00a0\u00a0Association of CD14 variant with prostate cancer in African American men.\u00a0Prostate.2010 Feb 15;70(3):262-9 Ricks-Santi L,\u00a0Mason T,\u00a0 Apprey V, Ahaghotu C,\u00a0 McLaughlin A,\u00a0 Josie D,\u00a0 Bonney G, Dunston GM,\u00a0Pro72Arg polymorphism and prostate cancer in men of African descent. 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