{"id":3889,"date":"2020-02-14T19:44:46","date_gmt":"2020-02-14T19:44:46","guid":{"rendered":"https:\/\/home.hamptonu.edu\/pharmacy\/?page_id=3889"},"modified":"2025-05-20T19:44:38","modified_gmt":"2025-05-20T19:44:38","slug":"dr-chengan-du-bio","status":"publish","type":"page","link":"https:\/\/home.hamptonu.edu\/pharmacy\/dr-chengan-du-bio\/","title":{"rendered":"Dr. Chengan Du Bio"},"content":{"rendered":"\t\t
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Dr. Chengan Du<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Associate Professor<\/em><\/p>

Location:\u00a0<\/strong>Biomedical Research Building II – Room 123<\/p>

Phone:<\/strong> 757-728-6692<\/p>

E-mail:<\/strong>\u00a0chengan.du@hamptonu.edu<\/a><\/p>

Expertise: <\/b>Pharmaceutics, Biopharmaceutics, Pharmaceutical Analysis and Proteomics<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Education<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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  • Ph.D. in Pharmaceutics, University of Tennessee at Memphis, Memphis, TN 38163, 1999<\/li>
  • Master’s Degree in Public Health (MPH), Yale University, School of Medicine, 1995<\/li>
  • Bachelor Degree in Pharmacy, Hubei Traditional Chinese Medical College, 1985<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Post Doctoral-Training<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Dr. Du, an assistant professor, had taught undergraduate Pharmaceutics\/Biopharmaceutics courses in the Zhejiang College of Traditional Chinese Medicine for nine years before his pursuing of Graduate Study at Yale and University of Tennessee. Dr. Du joined the faculty in Hampton University in 1999 and has been the course coordinator and lecturer for the Pharmaceutics\/Biopharmaceutics Course and has taught various selective courses. Dr. Du’s research interests are in the area of pharmaceutical proteomics and drug metabolism. He has several funded research projects. One of his research projects was funded by NIH\/NIDA to study human metabolism of illicit club drug MDMA (Ecstasy) using HPLC coupled with tandem mass spectrometer. Dr. Du has published a number of peer-reviewed research papers in renown scientific journals and has presented his research findings at several international conferences. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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    Grantsmanship<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    \u201cThe Electrospray of Paclitaxel nanoparticle for the treatment of Breast Cancer\u201d, Hampton University Faculty Grant, $10000, 2018-now<\/span>\u00a0<\/span>\u00a0<\/span><\/p>

    Polymeric Nanomedicines for Treating Cancers, Hampton University Faculty Research Grant <\/span> Co-Investigator, <\/span><\/b>01\/2012-01\/2013<\/span>\u00a0<\/span><\/p>

    ASBMB Proteomics and Bioinformatics Workshop Team Travel Award Period, April, 2006,\u00a0 Role: <\/span>Principal Investigator<\/span><\/b>, Amount: $5000 dollars<\/span>\u00a0<\/span><\/p>

    3 S06 GM066093-03S1<\/span>\u00a0<\/span><\/p>

    NATIONAL INSTITUTE ON GENERAL MEDICINE<\/span>\u00a0<\/span><\/p>

    Investigation of A<\/span><\/i>b<\/span><\/i> Peptide Levels and Structural Variants in Blood Serum of Patients with Alzheimer\u2019s Disease Using Nanoflow HPLC and Mass Spectrometry\u00a0<\/span><\/i>\u00a0<\/span><\/p>

    Period: 4\/30\/05-7\/30\/06, Release time: 25%<\/span>\u00a0<\/span><\/p>

    Role: <\/span>Principal Investigator<\/span><\/b>, Amount: $400,000<\/span>\u00a0<\/span><\/p>

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    1R24DA012546-1\u00a0\u00a0<\/span>\u00a0<\/span><\/p>

    \u00a0\u201cIn Vitro Study of the Metabolism of MDMA Using Human Hepatocytes\u201d\u00a0<\/span>\u00a0<\/span><\/p>

    NATIONAL INSTITUTE ON DRUG ABUSE<\/span>\u00a0<\/span><\/p>

    Period: 3\/30\/03-3\/30\/07, Release time: 10%<\/span>\u00a0<\/span><\/p>

    Role: <\/span>Principal Investigator<\/span><\/b>, Amount: $460,000<\/span>\u00a0<\/span><\/p>

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    5S06GM066093-03\u00a0<\/span>\u00a0<\/span><\/p>

    MBRS-SCORE Program at Hampton University<\/span>\u00a0<\/span><\/p>

    NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES<\/span>\u00a0<\/span><\/p>

    Role:\u00a0 <\/span>Co-Investigator<\/span><\/b>, Amount: $2,000000\u00a0 Total Cost,\u00a0 Status:\u00a0<\/span>\u00a0<\/span><\/p>

    04-SEP-2002- 31-AUG-2006<\/span>\u00a0<\/span><\/p>

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    5S06GM066093-03<\/span>\u00a0<\/span><\/p>

    MBRS-SCORE Instrument Supplement Support<\/span>\u00a0<\/span><\/p>

    NATIONAL INSTITUTE GENERAL MEDICAL SCIENCES<\/span>\u00a0<\/span><\/p>

    Role:<\/span> Co-Investigator<\/span><\/b>, Amount; $850,000 January 1, 2004 to December 30, 2004<\/span>\u00a0<\/span><\/p>

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    The Role of Cholesterol in the Development of Alzheimer\u2019 Disease (PI)<\/span>\u00a0<\/span><\/p>

    Hampton University Grant Award<\/span> \u00a0<\/span><\/p>

    Role: <\/span>Principal Investigator, <\/span><\/b>Amount: $6000, 2002-2003<\/span>\u00a0<\/span><\/p>

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    HPLC method development for Ab peptides, Hampton University Grant Award<\/span> \u00a0<\/span><\/p>

    Role: <\/span>Co-Investigator, <\/span><\/b>Amount: $5000, Status: 2004-2005<\/span>\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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    Selected Publications and Presentation<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Shunqi Shi, <\/span>Chengan Du<\/span><\/b> and Dihua Shian Study on the release rate of berberine from three different dosage form of Zuojin.<\/span> China Traditional Patent Medicine<\/span><\/i> 7<\/span><\/b>: 1-3 (1985).<\/span>\u00a0<\/span><\/p>

    \u00a0<\/span>Chengan Du<\/span><\/b> and Shunqi Shi. The relationship between release rate <\/span>in Vitro<\/span><\/i> and dosage form of solid preparation. <\/span>China Traditional Patent Medicine<\/span><\/i>\u00a0 <\/span>9<\/span><\/b>: 5-7 (1987).<\/span>\u00a0<\/span><\/p>

    \u00a0<\/span>Chengan Du<\/span><\/b> and\u00a0 Xianglin Yin. Inquiry on inclusion mechanism of rutin with cyclodextrin. <\/span>China Traditional Patent Medicine\u00a0 <\/span><\/i>11<\/span><\/b>: 9-13 (1989).<\/span>\u00a0<\/span><\/p>

    \u00a0<\/span>Chengan Du<\/span><\/b> and\u00a0 Xianglin Yin. Process improvement for Shen Mi oral liquid. <\/span>Journal Of<\/span><\/i> Chinese Materia Medica\u00a0 <\/span><\/i>16<\/span><\/b>: 28-33 (1991).<\/span>\u00a0<\/span><\/p>

    \u00a0<\/span>Xianglin Yang and <\/span>Chengan Du<\/span><\/b>. Study on amino acid release and dissolution rate for different\u00a0 product of manis pentadactyla. <\/span>China Traditional Patent<\/span><\/i> Medicine<\/span><\/i> 14<\/span><\/b>: 22-24 (1992)<\/span>\u00a0<\/span><\/p>

    \u00a0<\/span>Chengan Du<\/span><\/b>, Jennifer M.Ye and Janet L. Wolfe<\/span>. <\/span><\/b>Improved folding yields of a model protein using protein disulfide isomerase. <\/span>Pharmaceutical Research<\/span><\/i>, 15(12), 1808-1815 (1998).<\/span>\u00a0<\/span><\/p>

    \u00a0<\/span>Chengan Du<\/span><\/b> and Janet L. Wolfe. Mass balance of C125A rhIL-2 during oxidative during oxidative folding. <\/span>PharmSci<\/span><\/i>, <\/span>1<\/span><\/b>(1), S-537,\u00a0 (1998).<\/span>\u00a0<\/span><\/p>

    \u00a0<\/span>J.L. Wolfe, L. Thoma, <\/span>Chengan Du<\/span><\/b>, et al. Physical compatibility and chemical stability of vincristine sulfate, doxorubicin hydrochloride, and\u00a0 etoposide in 0.9% Sodium Chloride Injection, USP. <\/span>American Journal of Health-System Pharmacy<\/span><\/i>. 56 (10):\u00a0 (1999)\u00a0<\/span>\u00a0<\/span><\/p>

    \u00a0<\/span>Chengan Du<\/span><\/b>, J.L Wolfe, The inhibition mechanism of guanidine hydrochloride on catalytic activity of recombinant human protein disulfide isomerase,\u00a0\u00a0 <\/span>Journal of Enzyme Inhibition and Medicinal Chemistry<\/span><\/i>, 18 (1) 47-53, 2003<\/span>\u00a0<\/span><\/p>

    \u00a0<\/span>Chengan Du<\/span><\/b>, J.L Wolfe, Study of Recombinant Human Protein Disulfide Isomerase-Assisted C125A Recombinant Human Interleukin-2 Folding, <\/span>Biotechnology & Applied Biochemistry<\/span><\/i>, 37: 129-38, 2003\u00a0<\/span>\u00a0<\/span><\/p>

    \u00a0<\/span>Chengan Du<\/span><\/b>, C. Ramaley, H. McLean, S. Leonard, J. Miller.\u00a0 Detection of Abeta Peptide Associated with Alzheimer\u2019s Disease Using SEC\/RP-HPLC Coupled with Tandem Mass Spectrometry.\u00a0 Supplement to the AAPS Journal.\u00a0 Volume 6 (Issue S1): 1658, October 2004.<\/span>\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

    Dr. Chengan Du Associate Professor Location:\u00a0Biomedical Research Building II – Room 123 Phone: 757-728-6692 E-mail:\u00a0chengan.du@hamptonu.edu Expertise: Pharmaceutics, Biopharmaceutics, Pharmaceutical Analysis and Proteomics Education Ph.D. in Pharmaceutics, University of Tennessee at […]<\/p>\n","protected":false},"author":50,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_mc_calendar":[],"footnotes":""},"class_list":["post-3889","page","type-page","status-publish","hentry"],"yoast_head":"\nDr. Chengan Du Bio - 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