{"id":4539,"date":"2022-09-25T17:01:22","date_gmt":"2022-09-25T17:01:22","guid":{"rendered":"https:\/\/home.hamptonu.edu\/science\/?page_id=4539"},"modified":"2025-05-19T14:52:10","modified_gmt":"2025-05-19T18:52:10","slug":"oluwatoyin-asojo","status":"publish","type":"page","link":"https:\/\/home.hamptonu.edu\/science\/oluwatoyin-asojo\/","title":{"rendered":"Oluwatoyin Asojo"},"content":{"rendered":"\t\t
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Department of Chemistry and Biochemistry Faculty <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\"Dr. Dr. Oluwatoyin Ajibola Asojo<\/span> Chair, Chemistry and Biochemistry<\/span><\/span>
Location: <\/span>Turner Hall<\/span>223<\/span><\/span>
Phone: <\/span>757-727-5396<\/span><\/span>
E-mail: <\/span>oluwatoyin.asojo@hamptonu.edu<\/a><\/span><\/span>
Expertise: <\/span>Biochemistry, drug discovery, Biophysics, education, vaccines<\/span><\/span><\/p>

Dr. Oluwatoyin Asojo
<\/strong>Associate Professor, and Chair Chemistry and Biochemistry<\/em><\/p>

Location:<\/strong>Turner Hall 223<\/p>

Education:
<\/strong>PhD, 1999 University of Houston Texas
BSc with Honors, 1993 Trent University, Peterborough ON Canada<\/p>

Professional Positions Held\u00a0<\/strong>\u00a0
2018 – present \u00a0 \u00a0 \u00a0 \u00a0 Associate Professor, Hampton University, Department of Chemistry and Biochemistry, Hampton, VA<\/p>

2018 – 2019 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 Adjunct Associate Professor, Baylor College of Medicine, Houston, TX<\/p>

2012 – 2017\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Associate Professor, Baylor College of Medicine, National School of Tropical Medicine,\u00a0Houston, TX<\/p>

2005 – 2012\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Assistant Professor, University of Nebraska Medical Center, Pathology and Microbiology\u00a0Department, Omaha, NE<\/p>

2003 \u2013 2005\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Research Assistant Professor, University of Nebraska Medical Center, Eppley Research Institute, Omaha, NE<\/p>

2001 – 2003\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Research Fellow, National Cancer Institute, Frederick Cancer Research Center,Frederick, MD<\/p>

2000 – 2001\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Staff Scientist,\u00a0Tibotec-Virco, Rockville, MD<\/p>

Curricular Activities \/ Chemistry Courses taught:
<\/strong>Intermediate biochemistry, biophysical chemistry, introductory physical science, and general chemistry<\/p>

Research Interests and Expertise:
<\/strong>Chemistry of life processes:\u00a0deciphering the mechanisms and structural basis of immune and suppression evasion by infectious agents or host cells.\u00a0Developing improved methods for the recombinant expression, purification, solubilization and crystallization of proteins.\u00a0In silico<\/em>analysis of protein structure \/ function to guide functional studies of novel proteins,X-ray crystallography, biochemical, biophysical and functional analysis of macromolecules<\/p>

Links to my Research<\/strong><\/p>

https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=asojo%20o&sort=pubdate<\/p>

Open Researcher and Contributor ID<\/a>(ORCID)<\/p>

My Google Scholar Profile<\/a><\/p>

Selected Publications<\/strong><\/p>

1. Asojo OA*, Darwiche R, Gebremedhin S, Smant G, Lozano-Torres JL, Drurey C, Pollet J, Maizels RM, Schneiter R, Wilbers RHP.\u00a0Heligmosomoides polygyrus\u00a0<\/em>Venom Allergen-like Protein-4 (HpVAL-4) is a sterol binding protein. Int J Parasitol. 2018 Apr;48(5):359-369. PubMed PMID:\u00a029505764; PubMed Central PMCID:\u00a0PMC5893428.<\/p>

2. Darwiche R, Lugo F, Drurey C, Varossieau K, Smant G, Wilbers RHP, Maizels RM, Schneiter R, Asojo OA*. Crystal structure of\u00a0Brugia malayi\u00a0<\/em>venom allergen-like protein-1 (BmVAL-1), a vaccine candidate for lymphatic filariasis. Int J Parasitol. 2018 Apr;48(5):371-378. PubMed PMID:\u00a029501266; PubMed Central PMCID:\u00a0PMC5893361.\u00a0<\/p>

3. Liu Z, Kelleher A, Tabb S, Wei J, Pollet J, Hotez PJ, Bottazzi ME, Zhan B, Asojo OA*. Identification, Characterization, and Structure of Tm16 from\u00a0Trichuris muris<\/em>. J Parasitol Res. 2017;2017:4342789. PubMed PMID:\u00a028884022; PubMed Central PMCID:\u00a0PMC5573103.<\/p>

4. Asojo OA*. Structure of a two-CAP-domain protein from the human hookworm parasite\u00a0Necator\u00a0<\/em>americanus<\/em>. Acta Crystallogr D Biol Crystallogr. 2011 May;67(Pt 5):455-62. PubMed PMID:\u00a021543848; PubMed Central PMCID:\u00a0PMC3087624.<\/p>

5. Asojo OA*, Goud G, Dhar K, Loukas A, Zhan B, Deumic V, Liu S, Borgstahl GE, Hotez PJ. X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite,\u00a0Necator\u00a0<\/em>americanus<\/em>, and a vaccine antigen for human hookworm infection. J Mol Biol. 2005 Feb 25;346(3):801-14. PubMed PMID:\u00a015713464.<\/p>

6. Luo Z, Kelleher AJ, Darwiche R, Hudspeth EM, Shittu OK, Krishnavajhala A, Schneiter R, Lopez JE*,Asojo OA*. Crystal Structure of Borrelia turicatae\u00a0<\/em>protein, BTA121, a differentially regulated gene in the tick-mammalian transmission cycle of relapsing fever spirochetes. Sci Rep. 2017 Nov 10;7(1):15310. PubMed PMID:\u00a029127407; PubMed Central PMCID:\u00a0PMC5681642.<\/p>

7.\u00a0\u00a0Asojo OA*, Kelleher A, Liu Z, Pollet J, Hudspeth EM, Rezende WC, Groen MJ, Seid CA, AbdeladhimM, Townsend S, de Castro W, Mendes-Sousa A, Bartholomeu DC, Fujiwara RT, Bottazzi ME, Hotez PJ, Zhan B, Oliveira F, Kamhawi S, Valenzuela JG*. Structure of SALO, a leishmaniasis vaccine candidate from the sand fly\u00a0Lutzomyia longipalpis<\/em>. PLoS Negl Trop Dis. 2017 Mar;11(3):e0005374. PubMed PMID:\u00a028278244; PubMed Central PMCID:\u00a0PMC5344329.<\/p>

8. Kelleher A, Darwiche R, Rezende WC, Farias LP, Leite LC, Schneiter R, Asojo OA*.\u00a0Schistosoma\u00a0<\/em>mansoni\u00a0<\/em>venom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP\/TAPS protein that lacks the prototypical CAP motifs. Acta Crystallogr D Biol Crystallogr. 2014 Aug;70(Pt 8):2186-96. PubMed PMID:\u00a025084337; PubMed Central PMCID:\u00a0PMC4118828.<\/p>

9. Asojo OA*, Gulnik SV, Afonina E, Yu B, Ellman JA, Haque TS, Silva AM. Novel uncomplexed and complexed structures of plasmepsin II, an aspartic protease from\u00a0Plasmodium falciparum<\/em>. J Mol Biol. 2003 Mar 14;327(1):173-81. PubMed PMID:\u00a012614616.<\/p>

10. Asojo O, Friedman J*, Adir N, Belakhov V, Shoham Y, Baasov T*. Crystal structures of KDOP synthase in its binary complexes with the substrate phosphoenolpyruvate and with a mechanismbased inhibitor. Biochemistry. 2001 May 29;40(21):6326-34. PubMed PMID:\u00a011371194.<\/p>

Professional Honors and Awards<\/strong><\/p>