Dr. Chengan Du
Location: Biomedical Research Building II – Room 123
Expertise: Pharmaceutics, Biopharmaceutics, Pharmaceutical Analysis and Proteomics
- Ph.D. in Pharmaceutics, University of Tennessee at Memphis, Memphis, TN 38163, 1999
- Master’s Degree in Public Health (MPH), Yale University, School of Medicine, 1995
- Bachelor Degree in Pharmacy, Hubei Traditional Chinese Medical College, 1985
Dr. Du, an assistant professor, had taught undergraduate Pharmaceutics/Biopharmaceutics courses in the Zhejiang College of Traditional Chinese Medicine for nine years before his pursuing of Graduate Study at Yale and University of Tennessee. Dr. Du joined the faculty in Hampton University in 1999 and has been the course coordinator and lecturer for the Pharmaceutics/Biopharmaceutics Course and has taught various selective courses. Dr. Du’s research interests are in the area of pharmaceutical proteomics and drug metabolism. He has several funded research projects. One of his research projects was funded by NIH/NIDA to study human metabolism of illicit club drug MDMA (Ecstasy) using HPLC coupled with tandem mass spectrometer. Dr. Du has published a number of peer-reviewed research papers in renown scientific journals and has presented his research findings at several international conferences.
“The Electrospray of Paclitaxel nanoparticle for the treatment of Breast Cancer”, Hampton University Faculty Grant, $10000, 2018-now
Polymeric Nanomedicines for Treating Cancers, Hampton University Faculty Research Grant Co-Investigator, 01/2012-01/2013
ASBMB Proteomics and Bioinformatics Workshop Team Travel AwardPeriod, April, 2006, Role: Principal Investigator, Amount: $5000 dollars
3 S06 GM066093-03S1
NATIONAL INSTITUTE ON GENERAL MEDICINE
Investigation of Ab Peptide Levels and Structural Variants in Blood Serum of Patients with Alzheimer’s Disease Using Nanoflow HPLC and Mass Spectrometry
Period: 4/30/05-7/30/06, Release time: 25%
Role: Principal Investigator, Amount: $400,000
“In Vitro Study of the Metabolism of MDMA Using Human Hepatocytes”
NATIONAL INSTITUTE ON DRUG ABUSE
Period: 3/30/03-3/30/07, Release time: 10%
Role: Principal Investigator, Amount: $460,000
MBRS-SCORE Program at Hampton University
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Role: Co-Investigator, Amount: $2,000000 Total Cost, Status:
MBRS-SCORE Instrument Supplement Support
NATIONAL INSTITUTE GENERAL MEDICAL SCIENCES
Role: Co-Investigator, Amount; $850,000 January 1, 2004 to December 30, 2004
The Role of Cholesterol in the Development of Alzheimer’ Disease (PI)
Hampton University Grant Award
Role: Principal Investigator, Amount: $6000, 2002-2003
HPLC method development for Ab peptides, Hampton University Grant Award
Role: Co-Investigator, Amount: $5000, Status: 2004-2005
Selected Publications and Presentation
Shunqi Shi, Chengan Du and Dihua Shian Study on the release rate of berberine from three different dosage form of Zuojin. China Traditional Patent Medicine 7: 1-3 (1985).
Chengan Du and Shunqi Shi. The relationship between release rate in Vitro and dosage form of solid preparation. China Traditional Patent Medicine 9: 5-7 (1987).
Chengan Du and Xianglin Yin. Inquiry on inclusion mechanism of rutin with cyclodextrin. China Traditional Patent Medicine 11: 9-13 (1989).
Chengan Du and Xianglin Yin. Process improvement for Shen Mi oral liquid. Journal Of Chinese Materia Medica 16: 28-33 (1991).
Xianglin Yang and Chengan Du. Study on amino acid release and dissolution rate for different product of manis pentadactyla. China Traditional Patent Medicine 14: 22-24 (1992)
Chengan Du, Jennifer M.Ye and Janet L. Wolfe. Improved folding yields of a model protein using protein disulfide isomerase. Pharmaceutical Research, 15(12), 1808-1815 (1998).
Chengan Du and Janet L. Wolfe. Mass balance of C125A rhIL-2 during oxidative during oxidative folding. PharmSci, 1(1), S-537, (1998).
J.L. Wolfe, L. Thoma, Chengan Du, et al. Physical compatibility and chemical stability of vincristine sulfate, doxorubicin hydrochloride, and etoposide in 0.9% Sodium Chloride Injection, USP. American Journal of Health-System Pharmacy. 56 (10): (1999)
Chengan Du, J.L Wolfe, The inhibition mechanism of guanidine hydrochloride on catalytic activity of recombinant human protein disulfide isomerase, Journal of Enzyme Inhibition and Medicinal Chemistry, 18 (1) 47-53, 2003
Chengan Du, J.L Wolfe, Study of Recombinant Human Protein Disulfide Isomerase-Assisted C125A Recombinant Human Interleukin-2 Folding, Biotechnology & Applied Biochemistry, 37: 129-38, 2003
Chengan Du, C. Ramaley, H. McLean, S. Leonard, J. Miller. Detection of Abeta Peptide Associated with Alzheimer’s Disease Using SEC/RP-HPLC Coupled with Tandem Mass Spectrometry. Supplement to the AAPS Journal. Volume 6 (Issue S1): 1658, October 2004.